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If you need surgerytell the surgeon ahead of time that you are using ElavilYou may need to stop using the medicine for a short time. The pooled analyses of placebo-controlled trials in children and adolescents with MDDobsessive compulsive disorderOCDor other psychiatric disorders included a total of 24 short-term trials of 9 antidepressant drugs in over patientsThe pooled analyses of placebo-controlled trials in adults with MDD or other psychiatric disorders included a total of short-term trialsmedian duration of 2 monthsof 11 antidepressant drugs in over 77, patientsThere was considerable variation in risk of suicidality among drugsbut a tendency toward an increase in the younger patients for almost all drugs studiedThere were differences in absolute risk of suicidality across the different indicationswith the highest incidence in MDDThe risk differencesdrug vs placebohoweverwere relatively stable within age strata and across indicationsThese risk differencesdrug-placebo difference in the number of cases of suicidality per patients treatedare provided in Table 1.

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Antidepressants increased the risk compared to placebo of suicidal thinking and behavior suicidality in children, adolescents, and young adults in short-term studies of major depressive disorder MDD and other psychiatric disorders. Anyone considering the use of PAXIL or any other antidepressant in a child, adolescent, or young adult must balance this risk with the clinical need.