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Pyridostigmine is mainly excreted unchanged by the kidney6,7,8 Thereforelower doses may be required in patients with renal diseaseand treatment should be based on titration of drug dosage to effect6,7.

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It affects chemicals in the brain that may become unbalanced.

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Donepezil may improve the ability to think and remember or slow the loss of these abilities in people who have AD. It is usually taken once a day with or without food, in the evening just before bedtime.

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