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Clonidine was synthesized in as nasal decongestant, and marketed as antihypertensive in Since then, clonidine has been used by anaesthesiologists as an anaesthetic adjunct to provide increased perioperative cardiovascular and sympathoadrenal stability, to enhance general and regional anaesthesia, as well as sedation and analgesia. |
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Risperidone is partly metabolised by CYP2D6 to 9-hydroxyrisperidone which has two enantiomers with a similar pharmacological activity as risperidone. |
Diagnosis of schizophrenia involves ruling out other mental health disorders and determining that symptoms are not due to substance abuse, medication or a medical condition. Determining a diagnosis of schizophrenia may include |
A small number of children, teenagers, and young adults up to 24 years of age who took antidepressants 'mood elevators' such as escitalopram during clinical studies became suicidal thinking about harming or killing oneself or planning or trying to do so. |
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