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Reduces the secretion of hydrochloric acid in the stomach by specific inhibition of the proton pump in parietal cells.

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Esomeprazole is used to treat conditions where there is too much acid in the stomach. It is used to treat duodenal and gastric ulcers, erosive esophagitis, gastroesophageal reflux disease GERD, and Zollinger-Ellison syndrome, a condition wherein the stomach produces too much acid.

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Nexium belongs to a class of medications known as proton-pump inhibitors PPIs. Esomeprazole works by blocking acid production in the stomach.

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