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Currently it is approved in more than 80 countries worldwide but not in the US, where the Food and Drug Administration FDA has required additional safety and efficacy data for etoricoxib before it will issue approval. It was patented in and approved for medical use in Etoricoxib is indicated for the treatment of rheumatoid arthritis, psoriatic arthritis, osteoarthritis, ankylosing spondylitis, chronic low back pain, acute pain, and gout. Approved indications differ by country. Among the different functions exerted by PGs, their role in the inflammation cascade should be highlighted. Because of these results, some drugs were withdrawn from the market rofecoxib in September and valdecoxib in April Archived from the original on 3 August Analogue-based Drug Discovery. Indian Journal of Dermatology, Venereology and Leprology.

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